A choice of disease for studying vestibular compensation in man : the betahistine example
Abstract
The author proposes, as disease for the study of drugs activity on vestibular compensation mechanisms in man, a peripheral labyrinthine disease without spontaneous nystagmus of type II or III.
He evaluates the state of compensation by the evolution of static posturography parameters and by the score of Norre’s VHT (vestibular habituation training) during an observation period of 56 days with placebo or active drug in 46 patients.
the betahistine doesn’t interfere with these mechanisms.