Pharmacotherapy

Abstract Objectives: Rehabilitation of patients with balance disorders is a great challenge for physicians. The aim of our prospective study was to examine the results of combined vestibular rehabilitation treatment in different types of vestibular lesions (central dysfunction, unilateral and bilateral type of peripheral lesion). Methods The patients having chronic vertigo symptoms were treated with […]

Abstract: Ménière’s disease is a severe disorder of the inner ear. The disorder has several types: periodical type (40%), progressive type (27%), regressive type (20%) and a variable form (13%). The treatment of the acute attack is quite easy, it contains antiemetic, antihistamines and benzodiazepines. The interval therapy has no evidence based rules. The aims […]

ABSTRACT Objective: Efficacy and tolerability of the fixed combination cinnarizine 20mg/dimenhydrinate 40mg was compared to cinnarizine 50mg and dimenhydrinate 100mg in peripheral, central or mixed peripheral/central vertigo. Methods: 189 patients were randomized to receive 1 tablet of medication, 3 times daily, for 4 weeks. Vertigo (‘mean vertigo score’, MVS) and concomitant symptoms, balance (craniocorpography) and […]

ABSTRACT Background: Ménière’s disease (MD) is characterized by recurrent, sudden episodes of disabling vertigo. A previous randomized, controlled study demonstrated a high efficacy of a fixed combination of cinnarizine 20mg and dimenhydrinate 40mg (Arlevert®, tid.) in MD, with no statistically significant difference to betahistine (dimesylate salt, 12mg, tid). Objective: This post hoc analysis was performed […]

Tinnitus Therapy schedule developed by us, we based on the schema of the auditory via and on the cortico -striatum- thalamus -cortical control system. The selected medicine or neurotransmitter will be directed to regulating the neuronal hyperactivity or hypoactivity functions, depending on the topographical location of tinnitus. It is impossible to treat tinnitus by a […]

Sever type of tinnitus is very hard to treat because tinnitus is highly inked to emotional system, the limbic system. To treat it, therefore, all means such as life style intervention, consultation, medication, doctor’s rich successful experience and relaxation should be used. External electrical stimulation may be one of relaxation therapy and tinntius relieved once […]

Major neurootological complaints, which mostly need drug treatment, are: giddiness, dizziness, hearing loss and tinnitus. The neurootological differential diagnosis is the basis for planning the mostly supportive treatment of vertigo patients. In planning the therapy, we are utilizing a computerbased expert system CLAMEDEX for establishing the neurootological diagnosis through history, ORL inspection, ENG, calorics, rotatory […]

Vestibular Neuronitis was described in 1949 and 1952 by Dix and Hallpike. Two groups of patients were described, those with sudden seizures and sensations of blackout (since identified as having Vestibular Neuritis) and a second group with symptoms of disequilibrium and feelings of top heaviness or imbalance. The pathology was felt to be central to […]

For Meniere`s Disease (M.D.) patients, we are using Betahistin as standard therapy & additionally Urea or Acetazolamide for the attack periods, with good results. But in severe cases of invalidating M.D. causing extensive vertigo, we are using since 6 years labyrinth perfusion by a solution of Gentamycine and Betamethazon. Methods: After insertion of a large […]