The use of enoxaparin for the treatment of tinnitus.
Abstract
Microthrombotic vascular lesions could be the primary or secondary cause but, however, in most of the cases are at the base of the lesions of tinnitus. On those bases we consider that a therapy with enoxaparine has a wide field of action.
Two hundred cases of patients, who had suffered from tinnitus for at least two months, have been analyzed.
These were randomly assigned to two groups: in the first group enoxaparin was administered subcutaneously at a dose of 2000 I.U. twice a day for 10 days while the second group (control) received a placebo. Every day all patients underwent the following instrumental examinations: liminar tonal audiometry; otoacoustic emission with linear Click emission; otoacoustic products of distortion with MACRO system. Specifically excluded were patients with abnormal known coagulation.
On discharge all patients treated with enoxaparin presented both a subjective and objective improvement in symptoms.
No patient had side effects due to the treatments with enoxaparin and the functional results are good at all, much more if compared with the protocols of therapy previously used for those kind of diseases.
Looking at the causes of tinnitus we consider this type of treatment to be highly efficacious and innovative.
