ISSN 1612-3352

Editors in Chief

Prof. Dr. Claus F. Claussen, Neurootological Research Institute of the Research Society for Smell, Taste, Hearing and Equilibrium Disorders at Bad Kissingen (4-G-F). Bad Kissingen, Germany.
Dr. med. Julia M. Bergmann,
Dr. med. Guillermo O. Bertora,
Otoneuroophthalmological Neurophysiology,
Buenos Aires, Argentina.

Production Managers

Dr. med. Julia M. Bergmann,
Dr. med. Guillermo O. Bertora,
Otoneuroophthalmological Neurophysiology,
Buenos Aires, Argentina.

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Tinnitus neurotopography: pathways and areas studied through brain electric tomography (loreta)


Advances in basic research in neurosciences and the introduction of new non-invasive techniques, that make possible the detection of weak signals of the brain, have revolutionized diagnosis and treatment. The most often used methods for functional imaging of the human brain are positron emission tomography (PET) and functional magnetic resonance imaging (fMRI).
More recently, a growing number of studies have been published that make use of functional imaging methods based on the electroencephalogram (EEG) and the magnetoencephalogram (MEG).
We use in our laboratory the EEG register in 21 derivation channels. The use of a specialized software (LORETA) makes possible obtaining functional imaging of the brain in 2D and 3D. Studies have been carried out through – Low Resolution Brain Electric Tomography – LORETA – on the spatial distribution of Cortical Evoked Response Audiometry (CERA) and on the temporo-spatial distribution of brain electrical activity mapping in 40 patients with tinnitus. Results have been compared vs. 40 patients who have not shown tinnitus symptoms.
The study of temporal distribution through the brain electric tomography represents the opening of a new field in tinnitus treatment.
The existence of frontalization in all these patients and the involvement of the limbic area have been extensively demonstrated in tinnitus, but there is a very significant interindividual variation where different types of cerebral rhythms can be combined indicating, definitely, a hypofunction or hyperfunction of some neurotransmitters.

Keywords: Low Resolution Brain Electric Tomography, LORETA, Tinnitus, Brain mapping, Auditory Evoked Potentials.



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