The rithm of melatonin in dizziness a possible role in the genesis of this symptom?

Authors

Prof. Dr. Antonio Cesarani (Milan, Italy)
Dr. med. Dario Alpini (Milan, Italy)
Dr. med. G. Raponi (Milan, Italy)
Dr. med. G.P. Giordano (Milan, Italy)
Dr. med. F. Fraschini (Milan, Italy)

Proceedings

XXVIII Congress of the NES - Alghero - Italy

Topics

Neurootology
Equilibrium
Diseases
Neurootology
Equilibrium
Neurootology
Neurootologic therapy
Neurootology
Neurootology
Neurootologic therapy
Pharmacotherapy

Keywords

Cognitive disorders, Dizziness, Equilibrium, Melatonin.

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Abstract

THE ROLE OF THE VESTIBULAR SYSTEM IS TO INTEGRATE POLISENSORIAL CUES AND PROVIDE A CONTINUOS AND PRECISE REPRESENTATION EITHER OF THE BODY SHAPE (SEGMENTAL BODY ORIENTATION, THAT TO SAY PERCEPTION OF THE RECIPROCAL POSITION OF BODY SEGMENTS ) OR THE ORIENTATION OF THE BODY INTO THE ENVIRONMENT (SPATIAL ORIENTATION).
MELATONIN IS A NATURAL HORMONE SECRETED BY THE PINEAL GLAND AND CONNECTED WITH CYCLIC ACTIVITIES SUCH AS SEASONAL CHANGEMENT AND LIGHT-DARK SLEEP-WAKENESS RYTHMS
IT IS KNWOWN THAT THE CIRCADIAN RITHM OF MELATONIN IS SOMETIME ALTERATED IN CENTRAL NERVOUS SYSTEM DISEASES SUCH AS ALZHEIMER AND PARKINSON.
IT HAS BEEN POSTULATED THAT MELATONIN COULD PLAY A ROLE INTO THE COGNITIVE ALTERATIONS OF THESE PATHOLOGIES
THERE ARE CLINICAL EVIDENCES THAT RELEAVE THAT CIRCADIAN RITHMS ARE DISTURBED IN VERTIGO PATIENTS AND IT IS KNOWN THAT VESTIBULAR DISORDERS MAY INDUCE COGNITIVE DISTURBANCES IN MEMORY, ATTENTION, SPATIAL ORIENTATION