Bppv and vasopressine

Authors

Prof. Dr. Antonio Cesarani (Milan, Italy)
Prof. Dr. Saverio Capobianco (Sassari, Italy)
Dr. med. Stefania Barozzi (Milan, Italy)
Dr. med. A. Satta (Sassari, Italy)
Dr. med. M. Cau (Sassari, Italy)

Proceedings

XXVIII Congress of the NES - Alghero - Italy

Topics

Neurootology
Equilibrium
Diseases
Neurootology
Equilibrium
Neurootology

Keywords

BPPV, Vasopressine.

Download

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Abstract

The possible relationship between inner ear and vasopressin (AVP, ADH) has been hypothesized since twenty years ago
About ten years ago, in anaesthetized guinea pigs, we demonstrated that changes in the inner ear pressure modify plasma AVP (pAVP) level and AVP secretion with consequent changes in urine flow rate and osmolality : our experiment was performed in a group of anaesthetized Guinea pig, in which we acutely augmented (protocol 1) and decreased (protocol 2) the inner ear pressure, when the inner ear pressure was decreased, we observed an increase of plasmatic ADH values and urinary osmolarity, meanwhile the urinary flow rate decreased; whereas when the inner ear pressure was augmented, we observed opposite effects………