Sudden sensorineural hearing loss

The pathogenesis of sudden sensorineural hearing loss (SNHL) and tinnitus are still not well understood. Prompted by such observations, we implemented a protocol using sodium enoxaparin associated with a venovenous hemofiltration for treatment of sudden hearing loss and tinnitus. The venovenous hemofiltration selectively eliminates fibrinogen, low-density lipoprotein, cholesterol, triglycerides, lipoprotein and complement from the blood […]

Eighty patients with sudden hearing loss and seventy patients with a chronical cochlear function decreasing have been treated until now with intravenous infusion of a recombinant glycoprotein analogous tissutal plasminogen activator (rt-PA): 3mg dissolved in 250mg of physiological saline given every 12 hr intravenously. Specifically excluded were patients with abnormal known coagulation. No patient was […]