Therapy

The AIM of this investigation is to evaluate the effect of Betaserc – 16 and 8 mg on the patients (workers in the system of transport), with vascular auditory and vestibular disturbances.

This reports recommends the consideration of development of additional outcome measures to be used as a battery of subjective self-assessment questionnaires for patients with tinnitus. The goal is improved overall care for the tinnitus patient. The name of the battery of outcome questionnaires is TOP. Five existing outcome measurements have been incorporated into the profile […]

Eighty patients with sudden hearing loss and seventy patients with a chronical cochlear function decreasing have been treated until now with intravenous infusion of a recombinant glycoprotein analogous tissutal plasminogen activator (rt-PA): 3mg dissolved in 250mg of physiological saline given every 12 hr intravenously. Specifically excluded were patients with abnormal known coagulation. No patient was […]

The results of the use of clarion implants in 30 Indian patients have been evaluated. Cases included in the study were prelingual & postlingual patients where the cochlea was normal and prelingual patients where the cochlea had a Mondini defect or was ossified. It was found that multiple speech strategies available with the Clarion implant […]

Caroverine a quinoxaline derivative, with glutamate antagonistic activity was used for cochlear synaptic tinnitus. A pilot study was done first in 4 cases at our centre. Two cases with pure cochlear synaptic tinnitus responded well to Caroverine while other two cases had tinnitus due to middle ear pathology and did not respond. Encouraged by these […]

Microthrombotic vascular lesions could be the primary or secondary cause but, however, in most of the cases are at the base of the lesions of tinnitus. On those bases we consider that a therapy with enoxaparine has a wide field of action. Two hundred cases of patients, who had suffered from tinnitus for at least […]

The chemical element zinc has been in the last decades strongly studied. It is well known that it is present in some different structures of the Central Nervous System, acting as a co-factor of excitatory glutamatergic synapsis. Its function is not yet fully understood, but it seems to modulate the sensibility of glutamatergic post-sinaptic receptors […]

Some authors have postulate that sistemic zinc can be employed in the threatment of tinnitus, because a sub-clinical hypozincemia is suposed to promote this auditory disturbance. However, in the majority of the cases of tinnitus, this hypozincemia was not confirmed. There is not enough randomized studies that could show the relationship between zinc and tinnitus. […]

It has long been suspected that an important relationship exists between inner and outer hair cells, and that a disturbance of this relationship could lead to the phenomenon of tinnitus. The electromodel of the auditory system describes one mechanism of this inter-hair cell relationship. Following this model a mechanism exists, driven by mechanosensitive outer hair […]

We carried out a retrospective survey of 25 years of clinical experience with the use of clonazepam as a vestibular and tinnitus suppressant in the pharmacological treatment of vestibular or cochleovestibular disorders due to different causes.