Archives for Sensology and Neurootology in Science and Practice
We prospectively studied 48 otosclerosis patients over a 2-year interval. Forty-four had stapedotomy, and four had stapedectomy. Demographics, clinical history, and pre- and postoperative audiometry results were recorded. A questionnaire asking about tinnitus (intensity, pitch) and including a visual analog scale quantifying the degree (1–10) of annoyance caused by the tinnitus was completed pre- and […]
For this study we have selected tinnitus patients who suffer from tinnitus during their professional life. Therefore this group has undergone a therapeutic rehabilitation therapy for tinnitus with a programmed ameliorative improving therapy with guidance, exercise, instructions and special tinnitus rehab-program. As has been proved by vestibular evoked cortical potentials, together with charting by means […]
Programming of the speech-processors in children provided with Cochlear Implant causes sometimes problems, especially in very small children. This becomes important at this time as the implantation-age of the children decreases continuously. With Neural Response Telemetry (NRT) stands for the Nucleus ® 24 Cochlear Implant system a new principle of programming of the speech processor […]
Tinnitus affects nearly 50 million people in the United States, with a minority demonstrating marked functional impairment. Alterations of gamma aminobutyric acid (GABA) neuronal function and benzodiazepine receptor (BZR) function in particular have been implicated in the pathophysiology of severe, chronic tinnitus. The purpose of our study was to evaluate the distribution of BZR in […]
The literature does not report others therapeutic protocols for immune-mediated sensorineural hearing loss (IMSNHL) treatment with sodium enoxaparin or other kinds of unfractionated heparin: our decision to use enoxaparin was based both on the pathogenesis of this condition and on evaluation of the other classes of drugs currently used. Fifty patients, who had suffered from […]
Eighty patients with sudden hearing loss and seventy patients with a chronical cochlear function decreasing have been treated until now with intravenous infusion of a recombinant glycoprotein analogous tissutal plasminogen activator (rt-PA): 3mg dissolved in 250mg of physiological saline given every 12 hr intravenously. Specifically excluded were patients with abnormal known coagulation. No patient was […]
The results of the use of clarion implants in 30 Indian patients have been evaluated. Cases included in the study were prelingual & postlingual patients where the cochlea was normal and prelingual patients where the cochlea had a Mondini defect or was ossified. It was found that multiple speech strategies available with the Clarion implant […]
Caroverine a quinoxaline derivative, with glutamate antagonistic activity was used for cochlear synaptic tinnitus. A pilot study was done first in 4 cases at our centre. Two cases with pure cochlear synaptic tinnitus responded well to Caroverine while other two cases had tinnitus due to middle ear pathology and did not respond. Encouraged by these […]
Microthrombotic vascular lesions could be the primary or secondary cause but, however, in most of the cases are at the base of the lesions of tinnitus. On those bases we consider that a therapy with enoxaparine has a wide field of action. Two hundred cases of patients, who had suffered from tinnitus for at least […]
The chemical element zinc has been in the last decades strongly studied. It is well known that it is present in some different structures of the Central Nervous System, acting as a co-factor of excitatory glutamatergic synapsis. Its function is not yet fully understood, but it seems to modulate the sensibility of glutamatergic post-sinaptic receptors […]
