Pharmacotherapy

Two years ago the Vertigo Clinic started to operate in Limassol. The aim of authors’ investigations is researching vertigo-producing factors in Cypriot patients, and to follow up the results of our treatment protocols. During the last two years examination of 196 vertiginous patients was performed. The patients’ case history was documented by questionnaire, and a […]

The author proposes, as disease for the study of drugs activity on vestibular compensation mechanisms in man, a peripheral labyrinthine disease without spontaneous nystagmus of type II or III. He evaluates the state of compensation by the evolution of static posturography parameters and by the score of Norre’s VHT (vestibular habituation training) during an observation […]

During the last half century, medical developments have expedited an increase of expectation of life, all over the world. This extension of life has made that some pathologies that in former years were considered of low prevalence, nowadays they have become top priority for public health.

Transtympanic gentamicin administration has become a popular modality in the treatment of Ménière’s disease. This modality and other inner-ear medical therapy are gaining increased clinical and scientific attention.

Our goal was to attempt to establish neuropharmacological tinnitus control (i.e., relief) with medication directed to restoration of a deficiency in the g-aminobutyric acid – benzodiazepine – chloride receptor in tinnitus patients with a diagnosis of a predominantly central type tinnitus.

At the ear, nose, and throat clinic of the Third Medical Faculty at Charles University and at the Psychiatry Department of the Institute for Further Education of Physicians in Prague, we examined 25 patients with tinnitus accompanied by psychiatric disturbances and followed them up for at least 6 months.

We carried out a retrospective survey of 25 years of clinical experience with the use of clonazepam as a vestibular and tinnitus suppressant in the pharmacological treatment of vestibular or cochleovestibular disorders due to different causes.

In this report, we summarize our clinical experience with intratympanic dexamethasone treatment (IDT) for control of tinnitus.

In a randomized, double-blind clinical study, we evaluated the efficacy and tolerability of the fixed combination of cinnarizine, 20 mg, and dimenhydrinate, 40 mg (Arlevert [ARL]) in comparison to betahistine dimesylate (12 mg) in 82 patients suffering from Ménière’s disease for at least 3 months and showing the characteristic triad of symptoms (paroxysmal vertigo attacks, […]

The objective of this study is the supposition, verified through suitable hematochemical tests, of the co-presence in the etiopathogenesis of the Menière syndrome and/or in the labyrinth pathologies or hypacusia also of central/systemic microtoxicosis. We do not therefore exclude other well known hypotheses on the causality of these pathologies, but one finds, above all in […]